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Cotyledonoid dissecting leiomyoma, also known as a “grape-like” myoma or Sternberg tumor, is a particularly uncommon variant of uterine fibroma that imitates malignant gross characteristics; however this tumor is a benign neoplasm clinically and pathologically.The name cotyledonoid leiomyoma originates from the characteristic macroscopic appearance, which includes extrauterine dark red-brown, spongy, bulbous, exophytic masses, resembling the maternal face of the placenta [Smith CC et al. Clinically, most cases occur in women of reproductive age, presenting abnormal uterine bleeding and symptoms related to the presence of a pelvic mass. Although this tumor is a benign neoplasm, gross appearance and unusual growth pattern may mimic a malignant process.Histologic types which can be diagnosed: In most cases the cells are morphologically distinct from mesothelial cells.
Total abdominal hysterectomy with preservation of adnexa was performed (Figure 1).Univ., Head of Departament, Obstetric and Gynecology Departament, County Emergency Hospital Arad “Vasile Goldis” Western University Arad, Faculty of Medicine Abnormal uterine bleeding is a common gynaecological complaint, an important problem of menopause women’s health. Post menopausal bleeding is generally regarded as an ominous and serious alarm of genital pathologies. Some morphologic features can point to the site of origin of an adenocarcinoma.For example, abundant hollow spheres (‘cannonball’) are a common pattern in metastatic breast cancer (ductal carcinoma).
Such 'proliferation spheres' may also be present in metastatic ovarian carcinoma as well as in small cell lung carcinoma.